منابع مشابه
Adjuvant chemotherapy in the elderly.
Cancer is predominantly a disease of the elderly: approximately 60% of all tumors and two-thirds of cancer-related deaths occur in those over 65 years of age. This proportion will grow with the expected increase in the size of the older population in the coming decades. For example, if incidence rates remain constant, the number of elderly women diagnosed with breast cancer in the US will incre...
متن کاملAdjuvant chemotherapy
The authors treated 10 advanced renal cell carcinoma with circadian venous continuous infusion of 5-Fluoro 2-Deoxyuridine (FUDR). The drug was delivered by Medtronic Synchromed implantable pump in 14-day cycles alternating with 14-day intervals of physiologic saline infusion. Of the patient observed for at least 8 months (range: 8-32, median: 22.1) 1 showed progression. Circadian continuous cen...
متن کاملN0 colorectal cancer in the elderly: prognostic role of advanced age and correlation with adjuvant chemotherapy
Materials and methods 129 patients who underwent radical surgery for N0 colorectal cancer were selected and grouped into three age classes: <65 years, between 65 and 80, >80. A subpopulation of 44 patients with colorectal cancer in stage II was selected from the initial group for a comparison with a control population consisting of 63 patients who underwent radical surgery and adjuvant chemothe...
متن کاملEfficacy and toxicity of adjuvant chemotherapy in elderly patients with colorectal cancer: the ACCORE study
BACKGROUND Elderly patients with primary colorectal cancer (CRC) are less frequently treated with adjuvant chemotherapy than younger patients due to concerns regarding toxicity and efficiency. We investigated how age, performance status (PS) and comorbidity influence treatment outcomes. PATIENTS AND METHODS A retrospective single-centre study of 529 patients with stages II-III CRC treated wit...
متن کاملAdjuvant chemotherapy for colon cancer in the elderly: moving from evidence to practice.
With a median age at diagnosis of 71 years old and the aging of the US population, colon cancer commonly occurs in the elderly. Adjuvant chemotherapy has been standard of care for stage III disease following complete surgical resection since 1990, but insufficient numbers of patients over 75 years old are participating in clinical trials, and a disparity persists in the administration of standa...
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ژورنال
عنوان ژورنال: Annals of Oncology
سال: 2003
ISSN: 0923-7534
DOI: 10.1093/annonc/mdg740